Hsa_circ_0000190 Promotes NSCLC Cell Resistance to Cisplatin via the Modulation of the miR-1253/IL-6 Axis.
Hua HeTian LiPublished in: Analytical cellular pathology (Amsterdam) (2024)
Together, these data suggest that hsa_circ_0000190 can promote DDP chemoresistance in NSCLC cells through its ability to modulate miR-1253/IL-6 axis activity, highlighting a novel pathway that can be targeted in an effort to guide the more effective diagnosis and management of DDP-resistant tumors.
Keyphrases
- cell proliferation
- small cell lung cancer
- long non coding rna
- long noncoding rna
- induced apoptosis
- advanced non small cell lung cancer
- cell cycle arrest
- single cell
- electronic health record
- cell therapy
- cancer therapy
- brain metastases
- stem cells
- endoplasmic reticulum stress
- pi k akt
- machine learning
- drug delivery
- epidermal growth factor receptor
- deep learning
- data analysis