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Identification of Schistosoma haematobium and Schistosoma mansoni linear B-cell epitopes with diagnostic potential using in silico immunoinformatic tools and peptide microarray technology.

Arthur VengesaiMarble ManuwaHerald MidziMasimba MandeyaVictor MuleyaKeith MujeniIsaac ChipakoTakafira Mduluza
Published in: PLoS neglected tropical diseases (2024)
One peptide with a good diagnostic performance and nine peptides with acceptable diagnostic performances were identified using the immunoinformatic approach and peptide microarray validation. There is need for evaluation of the peptides with true negatives and a good standard positive reference.
Keyphrases
  • bioinformatics analysis
  • molecular docking
  • human health