Biological underpinnings of radiomic magnetic resonance imaging phenotypes for risk stratification in IDH wild-type glioblastoma.

Fangzhan GuanZilong WangYuning QiuYu GuoDongling PeiMinkai WangAoqi XingZhongyi LiuBin YuJingliang ChengXianzhi LiuYuchen JiDongming YanJing YanZhenyu Zhang

Published in: Journal of translational medicine (2023)

Our findings indicated that the prognostic radiomic phenotypes derived from conventional MRI are driven by distinct pathways involved in proliferation, DNA damage response, and immunity of IDH wild-type GBM.

Keyphrases

wild type
dna damage response
magnetic resonance imaging
contrast enhanced
dna repair
diffusion weighted imaging
computed tomography
signaling pathway
magnetic resonance
dna damage
high grade