Outcome of patients with colorectal cancer undergoing lung metastases resection: a single-institution retrospective analysis.
Marco MammanaFrancesca BergamoLetizia ProcaccioMarco SchiavonFotios LoupakisSara LonardiChiara ManaiMarta SchirripaMatteo FassanAngelo Paolo Dei TosFiorella CalabreseFederico ReaVittorina ZagonelPublished in: Tumori (2020)
This study shows particularly favorable survival outcomes for patients undergoing lung metastasectomy. The validity of some of the main prognostic factors was confirmed and a positive effect of postoperative chemotherapy on relapse-free survival was shown. Contrary to other reports, the presence of KRAS mutations was not associated with significant survival differences. Further studies are needed in order to clarify the interactions between molecular, clinical, and pathologic characteristics and treatment-related factors.