Eucalyptol Ameliorates Dysfunction of Actin Cytoskeleton Formation and Focal Adhesion Assembly in Glucose-Loaded Podocytes and Diabetic Kidney.
Dong Yeon KimMin-Kyung KangYun-Ho KimEun-Jung LeeHyeongjoo OhSoo-Il KimSu Yeon OhYoung-Hee KangPublished in: Molecular nutrition & food research (2019)
Eucalyptol ameliorates F-actin cytoskeleton formation and focal adhesion assembly through blockade of the Rho signaling pathway, entailing partial involvement of GSK3β, which may inhibit barrier dysfunction of podocytes and resultant proteinuria.
Keyphrases
- signaling pathway
- cell migration
- pi k akt
- oxidative stress
- mouse model
- wound healing
- high glucose
- biofilm formation
- diabetic nephropathy
- type diabetes
- drug delivery
- epithelial mesenchymal transition
- induced apoptosis
- cancer therapy
- endothelial cells
- protein kinase
- blood pressure
- escherichia coli
- metabolic syndrome
- skeletal muscle
- cell proliferation
- pseudomonas aeruginosa
- staphylococcus aureus
- candida albicans
- cell adhesion
- endoplasmic reticulum stress