Abdominal vagus nerve stimulation as a new therapeutic approach to prevent postoperative ileus.
Nathalie StakenborgA M WolthuisP J Gomez-PinillaG FarroM Di GiovangiulioG BosmansE LabeeuwM VerhaegenI DepoortereA D'HooreG MatteoliG E BoeckxstaensPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2017)
Abdominal VNS is feasible and safe in humans and has anti-inflammatory properties. As abdominal VNS improves POI similar to cervical VNS in mice, our data indicate that peroperative abdominal VNS may represent a novel approach to shorten POI in man.