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Gregarine single-cell transcriptomics reveals differential mitochondrial remodeling and adaptation in apicomplexans.

Eric D SalomakiKristina X TerpisSonja RueckertMichael KotykZuzana Kotyková VaradínováIvan ČepičkaChristopher E LaneMartin Kolísko
Published in: BMC biology (2021)
Apicomplexan lineages show variable functional restructuring of mitochondrial metabolism that appears to have been driven by adaptations to parasitism and anaerobiosis. Our findings indicate that apicomplexans are rife with convergent adaptations, with shared features including morphology, energy metabolism, and intracellularity.
Keyphrases
  • single cell
  • oxidative stress
  • rna seq
  • high intensity
  • high throughput