Association of baseline vitamin D level with genetic determinants and virologic response in patients with chronic hepatitis B.

Rui YuDeming TanQin NingJunqi NiuXuefan BaiShijun ChenJun ChengYanyan YuHao WangMin XuGuangfeng ShiMobin WanXinyue ChenHong TangJifang ShengXiaoguang DouJunping ShiHong RenMaorong WangHongfei ZhangZhiliang GaoChengwei ChenHong MaJidong JiaJinlin HouQing XieJian Sun

Published in: Hepatology research : the official journal of the Japan Society of Hepatology (2017)

Vitamin D insufficiency was highly prevalent in treatment-naïve CHB patients in mainland China. Latitude and genetic determinants affect vitamin D status. Baseline vitamin D level can predict week-104 virologic response, but not HBeAg seroconversion or ALT normalization.

Keyphrases

hepatitis b virus
end stage renal disease
newly diagnosed
hiv infected
chronic kidney disease
genome wide
ejection fraction
antiretroviral therapy
prognostic factors
peritoneal dialysis
copy number
clinical trial
liver fibrosis
placebo controlled