Long read sequencing reveals novel isoforms and insights into splicing regulation during cell state changes.

David J WrightNicola A L HallNaomi IrishAngela L ManWill GlynnArne MouldAlejandro De Los AngelesEmily AngioliniDavid SwarbreckKarim GharbiElizabeth M TunbridgeWilfried Haerty

Published in: BMC genomics (2022)

Our work highlights the potential of long read sequencing to uncover previously unknown transcript diversity and mechanisms influencing alternative splicing.

Keyphrases

single cell
rna seq
single molecule
cell therapy
human health
climate change