Computed tomographic assessment of lung aeration at different positive end-expiratory pressures in a porcine model of intra-abdominal hypertension and lung injury.
Adrian RegliSiavash Ahmadi-NoorbakhshGabrielle Christine MuskDavid Joseph ReesePeter HerrmannMartin Joseph FirthJ Jane PillowPublished in: Intensive care medicine experimental (2021)
Our findings in a large animal model suggest that titrating a PEEP to respiratory mechanics or oxygenation in the presence of IAH is associated with increased alveolar overdistension.