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Discordant pattern of peripheral fractures in diabetes: a meta-analysis on the risk of wrist and ankle fractures.

Tatiane VilacaJ WalshR Eastell
Published in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2018)
The risk of fractures is increased in diabetes at the ankle and decreased at the wrist. The same pattern is observed in obesity. Although bone microarchitectural features are different in obesity and diabetes, the epidemiology of peripheral fractures is similar in both diseases suggesting that microarchitecture may not be the major determinant of peripheral fractures in these populations.
Keyphrases
  • type diabetes
  • cardiovascular disease
  • glycemic control
  • metabolic syndrome
  • insulin resistance
  • weight loss
  • chemotherapy induced
  • risk factors
  • bone mineral density
  • body mass index
  • soft tissue