Steroidogenesis in patients with adrenal incidentalomas: Extended steroid profile measured by liquid chromatography-mass spectrometry after ACTH stimulation and dexamethasone suppression.

Martha Katherine P HuayllasLynette M SmithJ Christopher GallagherBrian C NetzelRavinder J SinghClaudio E Kater

Published in: Clinical endocrinology (2021)

There is increased activity in several steroid biosynthesis pathways and higher steroid levels in bilateral compared to unilateral cases and evidence of hypercortisolism in 30% unilateral and 62% of bilateral incidentalomas.

Keyphrases

liquid chromatography
mass spectrometry
high resolution mass spectrometry
tandem mass spectrometry
case report
low dose
high performance liquid chromatography
simultaneous determination
gas chromatography
high resolution
high dose