MiR-218-5p/EGFR Signaling in Arsenic-Induced Carcinogenesis.
Ranakul IslamLei ZhaoXiujuan ZhangLing-Zhi LiuPublished in: Cancers (2023)
Our study highlights the vital role of the miR-218-5p/EGFR signaling pathway in arsenic-induced carcinogenesis and angiogenesis, which may be helpful for the treatment of lung cancer induced by chronic arsenic exposure in the future.
Keyphrases
- drinking water
- small cell lung cancer
- high glucose
- signaling pathway
- diabetic rats
- epidermal growth factor receptor
- heavy metals
- tyrosine kinase
- endothelial cells
- drug induced
- oxidative stress
- epithelial mesenchymal transition
- vascular endothelial growth factor
- risk assessment
- cell proliferation
- induced apoptosis
- smoking cessation
- replacement therapy