Effects of toxic apolipoprotein E fragments on Tau phosphorylation and cognitive impairment in neonatal mice under sevoflurane anesthesia.

Yang YuMan YangXiaoli ZhuangJiacheng PanYue ZhaoYonghao Yu

Published in: Brain and behavior (2022)

These data suggest that elevated ApoE fragments rather than full-length ApoE might be one of the underlying mechanisms of age-dependent Tau phosphorylation and cognitive impairment in young mice following sevoflurane anesthesia.

Keyphrases

cognitive impairment
high fat diet induced
cognitive decline
high fat diet
cerebrospinal fluid
protein kinase
type diabetes
wild type
adipose tissue
artificial intelligence