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Gender-based differences in platelet function and platelet reactivity to P2Y12 inhibitors.

Marco RanucciTommaso AloisioUmberto Di DeddaLorenzo MenicantiCarlo de VincentiisEkaterina Baryshnikovanull null
Published in: PloS one (2019)
Our findings confirm that women have a larger platelet count than men, and that this is associated to a trend towards a higher platelet reactivity. HTPR is largely represented in women with a high platelet count. This generates the hypothesis that women requiring P2Y12 inhibitors could potentially benefit from larger doses of drug or should be treated with anti-platelet agents with a low rate of HTPR.
Keyphrases
  • polycystic ovary syndrome
  • type diabetes
  • mental health
  • emergency department
  • adipose tissue
  • peripheral blood
  • middle aged
  • newly diagnosed
  • adverse drug
  • electronic health record