PD1 blockade alters cell-cycle distribution and affects 3'-deoxy-3'-[ 18 F]fluorothymidine uptake in a mouse CT26 tumor model.

Motofumi SuzukiTakuma MatsudaKohei NakajimaYuta YokouchiYuji KugeMikako Ogawa

Published in: Annals of nuclear medicine (2022)

F]FLT is taken up by tumor cells even if tumor proliferation is suppressed. This observation may be useful for evaluating the response to immunotherapy.

Keyphrases

cell cycle
cell proliferation
acute myeloid leukemia
computed tomography
signaling pathway
tyrosine kinase
magnetic resonance imaging
dual energy
positron emission tomography