Acceleration and suppression of resistance development by antibiotic combinations.
Shingo SuzukiTakaaki HorinouchiChikara FurusawaPublished in: BMC genomics (2017)
Integration of laboratory evolution and whole-genome sequencing enabled us to characterize the development of resistance in bacteria under combination therapy. These results provide a basis for rational selection of antibiotic combinations that suppress resistance development effectively.
Keyphrases