Haptoglobin gene diversity and incidence of uncomplicated malaria among children in Iganga, Uganda.

Catherine N LwaniraFred KirondeGöte Swedberg

Published in: Malaria journal (2020)

This study showed that the Hp 1-1 and Hp 2-1 genotypes each occur in nearly 4 in 10 children and the Hp 2-2 genotype occurs in 2 of every 10 children. No association with incidence of uncomplicated malaria was found. Additional studies of influence of haptoglobin genotypes on P. falciparum malaria severity are needed to understand the role of these genotypes in malarial protection.

Keyphrases

plasmodium falciparum
young adults
gene expression
genome wide
copy number