Letrozole concentration is associated with CYP2A6 variation but not with arthralgia in patients with breast cancer.
Adrienne E BorrieRhiannon V RoseYun-Hee ChoiFrancisco E PereraNancy ReadTracy SextonMichael LockTheodore A VandenbergKarin HahnRobert DinniwellJawaid YounusDiane LoganKylea PotvinBrian YaremkoEdward YuJohn LenehanStephen WelchRachel F TyndaleWendy A TeftRichard B KimPublished in: Breast cancer research and treatment (2018)
CYP2A6 genotype was a significant predictor of letrozole plasma levels, but was not associated with the development of arthralgia.