Evaluation of Cerebrospinal Fluid α-Synuclein Seed Amplification Assay in Progressive Supranuclear Palsy and Corticobasal Syndrome.
David P VaughanRiona FumiMarte Theilmann JensenMegan HodgsonTatiana GeorgiadesLesley WuDanielle LuxRuth ObrockiJennifer LamoureuxOlaf AnsorgeKieren S J AllinsonThomas Treharne WarnerZane JaunmuktaneAnjum MisbahuddinP Nigel LeighBoyd C P GhoshKailash P BhatiaAlistair ChurchChristopher KobyleckiMichele T M HuJames Benedict RoweCornelis BlauwendraatHuw R MorrisEdwin JabbariPublished in: Movement disorders : official journal of the Movement Disorder Society (2024)
Our results suggest that α-synuclein seeds can be detected in PSP and CBS using a cerebrospinal fluid α-synuclein SAA, and in PSP this may impact on clinical course. © 2024 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.