FGF21 promotes migration and differentiation of epidermal cells during wound healing via SIRT1-dependent autophagy.

Xixi ChenGaozan TongJunfu FanYingjie ShenNan WangWenjie GongZijing HuKunxuan ZhuXiaokun LiLi-Tai JinWeitao CongZhou-Guang WangZhongxin Zhu

Published in: British journal of pharmacology (2021)

FGF21 is a key regulator of keratinocyte migration and differentiation during wound healing. FGF21 may be a novel therapeutic target to accelerate would healing.

Keyphrases

wound healing
induced apoptosis
oxidative stress
endoplasmic reticulum stress
cell cycle arrest
cell death
signaling pathway
cell proliferation