Effect of diabetes on exosomal miRNA profile in patients with obesity.
Hyoshik KimYun-Ui BaeHaekyung LeeHyoungnae KimJin Seok JeonHyunjin NohDong Cheol HanDong Won ByunSang Hyun KimHyeong Kyu ParkSeongho RyuSoon Hyo KwonPublished in: BMJ open diabetes research & care (2021)
Our data show that the exosomal miRNAs is altered by dysregulated glucose metabolism in patients with obesity. This circulating exosomal miRNA signature in patients with obesity with or without DM is a potential biomarker and therapeutic target in these patients.
Keyphrases
- type diabetes
- insulin resistance
- metabolic syndrome
- weight loss
- high fat diet induced
- weight gain
- end stage renal disease
- ejection fraction
- glycemic control
- chronic kidney disease
- prognostic factors
- cardiovascular disease
- peritoneal dialysis
- body mass index
- machine learning
- physical activity
- patient reported outcomes
- deep learning
- patient reported