How to handle a delayed or missed dose of edoxaban in patients with non-valvular atrial fibrillation? A model-informed remedial strategy.

Wei-Wei Lin Xiao-Qin LiuJia-Qin GuZi-Ran Li Zheng Jiao

Published in: British journal of clinical pharmacology (2022)

PK/PD modelling and simulation are effective in developing and evaluating the remedial strategies of edoxaban, which can help maximise its therapeutic effect.

Keyphrases

atrial fibrillation
venous thromboembolism
oral anticoagulants
direct oral anticoagulants
left atrial
catheter ablation
left atrial appendage
heart failure
percutaneous coronary intervention
aortic valve
coronary artery disease