Diffusion prepared pseudo-continuous arterial spin labeling reveals blood-brain barrier dysfunction in patients with CADASIL.
Chen LingJinyuan ZhangXingfeng ShaoLi BaiZhixin LiYunchuang SunFan LiZhaoxia WangRong XueYan ZhuoQi YangZihao ZhangDanny J J WangYun YuanPublished in: European radiology (2023)
• DP-pCASL reveals blood-brain barrier dysfunction in patients with CADASIL. • Decreased BBB water exchange rate, an indicator of BBB dysfunction detected by DP-pCASL, was associated with MRI/clinical features of patients with CADASIL. • DP-pCASL can be used as an evaluation method to assess the severity of disease in patients with CADASIL.