Kamebakaurin Suppresses Antigen-Induced Mast Cell Activation by Inhibition of FcεRI Signaling Pathway.

Haruka AsaiKoichi KatoMayu MiyasakaKaho HatsukawaNanami MurakamiNaoko TakedaJunna AbeYutaka AoyagiYuka KohdaMing-Yu GuiYong-Ri JinXu-Wen LiYukio HitotsuyanagiKoichi TakeyaTsugunobu AndohHiromasa KurosakiNobuyuki Fukuishi

Published in: International archives of allergy and immunology (2024)

Kamebakaurin ameliorates allergic symptoms via inhibition of Syk phosphorylation; thus, kamebakaurin could be a lead compound for the new anti-allergic drug.

Keyphrases

signaling pathway
pi k akt
drug induced
tyrosine kinase
diabetic rats
epithelial mesenchymal transition
mouse model
induced apoptosis
atopic dermatitis
physical activity
adverse drug
cell proliferation
electronic health record