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Evaluation of mRNA-1273 Covid-19 Vaccine in Children 6 to 11 Years of Age.

C Buddy CreechLarry J AndersonVladimir BerthaudInci YildirimAndrew M AtzIvan Melendez BaezDaniel FinkelsteinPaul PickrellJudith KirsteinClifford YutRonald BlairRobert A CliffordMichael DunnJames D CampbellDavid C MontefioriJoanne E TomassiniXiaoping ZhaoWeiping DengHonghong ZhouDaniela Ramirez SchremppKelly HautzingerBethany GirardKaren SlobodRoderick McPheeRolando PajonRituparna DasJacqueline M MillerSabine Schnyder Ghamloushnull null
Published in: The New England journal of medicine (2022)
Two 50-μg doses of the mRNA-1273 vaccine were found to be safe and effective in inducing immune responses and preventing Covid-19 in children 6 to 11 years of age; these responses were noninferior to those in young adults. (Funded by the Biomedical Advanced Research and Development Authority and the National Institute of Allergy and Infectious Diseases; KidCOVE ClinicalTrials.gov number, NCT04796896.).
Keyphrases
  • young adults
  • infectious diseases
  • coronavirus disease
  • sars cov
  • immune response
  • binding protein
  • respiratory syndrome coronavirus
  • quality improvement
  • toll like receptor
  • dendritic cells