Bintrafusp alfa, a bifunctional fusion protein targeting TGF-β and PD-L1, in advanced squamous cell carcinoma of the head and neck: results from a phase I cohort.

Byoung Chul ChoAmaury DasteAlain RavaudSébastien SalasNicolas IsambertEdward McClayAhmad AwadaChristian BorelLaureen S OjalvoChristoph HelwigP Alexander RolfeJames L GulleyNicolas Penel

Published in: Journal for immunotherapy of cancer (2021)

NCT02517398.

Keyphrases

squamous cell carcinoma
transforming growth factor
cancer therapy
replacement therapy
highly efficient
locally advanced
metal organic framework
drug delivery
radiation therapy
signaling pathway