Staphylococcus aureus-Associated Glomerulonephritis and Chronic Granulomatous Disease in an Adolescent Male.
Simon Parzen-JohnsonVidhi DalalRavi JhaveriPublished in: Journal of the Pediatric Infectious Diseases Society (2022)
Staphylococcus-associated glomerulonephritis (GN) is an uncommon diagnosis in pediatric patients. Empiric therapy with steroids alone could potentially worsen the underlying infectious process in these patients, leading to worse clinical outcomes. An adolescent male diagnosed with GN was subsequently found to have chronic granulomatous disease with a Staphylococcus aureus liver abscess. His GN improved with antibiotics alone. This case illustrates the need to consider chronic infection, and primary immunodeficiency, in the differential diagnosis for new-onset GN.
Keyphrases
- staphylococcus aureus
- young adults
- end stage renal disease
- biofilm formation
- mental health
- ejection fraction
- chronic kidney disease
- newly diagnosed
- prognostic factors
- methicillin resistant staphylococcus aureus
- interstitial lung disease
- rheumatoid arthritis
- cell therapy
- idiopathic pulmonary fibrosis
- candida albicans
- childhood cancer