Tumour-derived small extracellular vesicles contribute to the tumour progression through reshaping the systemic immune macroenvironment.
Zhimin DuHui ZhangYueyuan FengDewen ZhanShuya LiChenggong TuJin-Bao LiuJinheng WangPublished in: British journal of cancer (2023)
These results highlight that tumour-derived sEVs function as a bridge between peripheral immunity regulation and the tumour microenvironment, and contribute to cancer progression through altering the composition and function of the global immune macroenvironment.