Key Fabrications of Chitosan Nanoparticles for Effective Drug Delivery Using Flow Chemistry Reactors.
Kampanart HuanbuttaPornsak SriamornsakKittipat SuwanpitakNattapat KlinchuenThanapat DeebugkumVasanchai TeppitakTanikan SangnimPublished in: International journal of nanomedicine (2023)
The findings of this study indicate that the use of novel design flow chemistry reactor is promising for synthesizing clindamycin-loaded chitosan nanoparticles and other polymeric nanoparticles intended for drug delivery applications. This is primarily attributed to their ability to produce nanoparticles with a considerably reduced particle size distribution and smaller overall size. The demonstrated high productivity of this technique suggests the potential for industrial-scale nanoparticle manufacturing.