Genetic Polymorphisms in Genes Involved in the Type I Interferon System (IFIH1/MDA-5, TNFAIP3/A20, and STAT4): Association with SLE Risk in Egyptian Children and Adolescents.

Mohamed M ZedanZeinab Rizk AttiaRania A Abd El AzeemThuraya M MutawiAmora S El ShehawyAshraf Bakr

Published in: Journal of inflammation research (2021)

Our findings indicated that rs3747517 in IFIH1 was protective for SLE in Egyptian children and adolescents. Moreover, rs7574865 in STAT4 not rs610604 in TNFAIP3 was associated with SLE risk.

Keyphrases

systemic lupus erythematosus
disease activity
cell proliferation
breast cancer cells
signaling pathway