Comparative Studies of Renin-Null Zebrafish and Mice Provide New Functional Insights.

Scott HoffmannLinda J MullinsSebastien RiderCara BrownCharlotte B BuckleyAdrienne M Assmus Ziwen LiMariana Sierra BeltranNeil HendersonJorge Del PozoAlexandre De Goes MartiniMaria Luisa Soledad Sequeira-LopezR Ariel GomezJohn Mullins

Published in: Hypertension (Dallas, Tex. : 1979) (2022)

Phenotypic similarities and transcriptional variations between mouse and zebrafish renin knockouts suggests evolution of renin cell function with terrestrial survival.

Keyphrases

angiotensin converting enzyme
gene expression
transcription factor
angiotensin ii
high fat diet induced
adipose tissue
oxidative stress
metabolic syndrome
insulin resistance
heat shock protein