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Current advances in immune checkpoint inhibitor combinations with radiation therapy or cryotherapy for breast cancer.

Alice Y HoShervin TabriziSamantha A DunnHeather L McArthur
Published in: Breast cancer research and treatment (2021)
RT and cryotherapy are local therapies that can be integrated safely with ICI and has shown promise in early trials. Randomized phase II studies testing both of these approaches, such as P-RAD (NCT04443348) and ipilimumab/nivolumab/cryoablation for TNBC (NCT03546686) are current enrolling. The results of these studies are paramount as they will provide long term data on the safety and efficacy of these regimens.
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