Megacities, migration and an evolutionary approach to bipolar disorder: a study of Sardinian immigrants in Latin America.

Mauro Giovanni CartaMaria F MoroMartina PirasVanessa LeddaEleonora PrinaSerena StocchinoGermano OrrùFerdinando RomanoMaria V BrasescoRafael C FreireAntonio Egidio NardiLeonardo Tondo

Published in: Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) (2020)

The higher frequency of hypomania in migrant populations appears to favor an evolutionary view in which mood disorders may be a maladaptive aspect of a genetic background with adaptive characteristics.

Keyphrases

bipolar disorder
genome wide
major depressive disorder
dna methylation
copy number
gene expression
genetic diversity
sleep quality