Chronic pancreatitis: an overview of diagnosis and management.
Theodor VoiosuGuido CostamagnaAndrea TringaliGiuseppe QueroAndrei VoiosuGuido CostamagnaPublished in: Expert review of gastroenterology & hepatology (2020)
The traditional challenges in managing chronic pancreatitis patients stemmed from the limitations of diagnostic modalities, which could not correctly identify patients in an early stage of the disease, as well as from the scarcity of therapeutic options available. Advances in imaging of CT-scan, MRI, and EUS have opened the way for early diagnosis and staging. This has allowed more aggressive and tailored therapeutic modalities, particularly in endoscopic therapy and minimally invasive surgical interventions. Although high-quality data from large RCTs is still scarce, evidence-based algorithms for diagnosis and therapy are now changing the way we address this chronic disease. In the near future, we can expect a tailored approach based on patient and disease-related predictive factors, relying on a vast armamentarium of endoscopic and surgical solutions.
Keyphrases
- end stage renal disease
- early stage
- ejection fraction
- newly diagnosed
- minimally invasive
- chronic kidney disease
- magnetic resonance imaging
- computed tomography
- prognostic factors
- stem cells
- high resolution
- radiation therapy
- deep learning
- patient reported outcomes
- mesenchymal stem cells
- electronic health record
- smoking cessation
- big data
- mass spectrometry
- sentinel lymph node
- neoadjuvant chemotherapy
- fine needle aspiration