Huoxue Jiedu Huayu Formula Alleviates Cell Pyroptosis in Contralateral Kidneys of 6-Month-Old UUO Rats through the NLRP3/Caspase-1/IL-1β Pathway.

Xuelian MaPanpan QiangGege ChenZheng WangXiangting WangQingyou Xu

Published in: Evidence-based complementary and alternative medicine : eCAM (2021)

HJHF and spirolactone inhibited excessive activation of MR and then reduced cell pyroptosis, which was dependent on the NLRP3/caspase-1/IL-1β pathway, to protect the contralateral kidneys of 6-month-old UUO rats.

Keyphrases

nlrp inflammasome
single cell
cell death
cell therapy
induced apoptosis
magnetic resonance imaging
magnetic resonance
weight gain
stem cells
body mass index
computed tomography
mesenchymal stem cells
physical activity
human milk
endoplasmic reticulum stress
contrast enhanced
signaling pathway