Application of high-resolution genomic profiling in the differential diagnosis of liposarcoma.

Magdalena KoczkowskaBeata Stefania Lipska-ZiętkiewiczMariola IliszkoJanusz RyśMarkku MiettinenJerzy LasotaWojciech BiernatAgnieszka Harazin-LechowskaAnna KruczakJanusz Limon

Published in: Molecular cytogenetics (2017)

Our findings show that the application of array-CGH allows to delineate clearly the genomic profiles of WDLPS, DDLPS and MLPS that reflect biological differences between these tumors. Although CNAs varied widely, the subtypes of tumors have characteristic genomic profiles that could facilitate the differential diagnosis of LPS subtypes, especially between WDLPS and DDLPS.

Keyphrases

high resolution
copy number
high throughput
single cell
high density