Probing astroglia with carbon nanotubes: modulation of form and function.
Manoj K GottipatiAlexei VerkhratskyVladimir ParpuraPublished in: Philosophical transactions of the Royal Society of London. Series B, Biological sciences (2015)
Carbon nanotubes (CNTs) have shown much promise in neurobiology and biomedicine. Their structural stability and ease of chemical modification make them compatible for biological applications. In this review, we discuss the effects that chemically functionalized CNTs, applied as colloidal solutes or used as strata, have on the morpho-functional properties of astrocytes, the most abundant cells present in the brain, with an insight into the potential use of CNTs in neural prostheses.
Keyphrases
- carbon nanotubes
- induced apoptosis
- cell cycle arrest
- white matter
- resting state
- quantum dots
- molecular dynamics simulations
- endoplasmic reticulum stress
- big data
- signaling pathway
- risk assessment
- human health
- functional connectivity
- cerebral ischemia
- machine learning
- blood brain barrier
- climate change
- high resolution
- deep learning
- solid phase extraction