Understanding the Artemia Salina (Brine Shrimp) Test: Pharmacological Significance and Global Impact.
Dionisio A OlmedoYelkaira VasquezJuan Antonio MoránEstela Guerrero De LeónCatherina Caballero-GeorgePablo N SolísPublished in: Combinatorial chemistry & high throughput screening (2023)
BST is a simple, affordable, benchtop assay, capable of detecting cytotoxic drugs with specific mechanisms of action, such as protein synthesis inhibition, antimitotic, DNA binding, topoisomerase I inhibitors, and caspases cascade interfering drugs. The microwell BST is a technique that is used worldwide for the bio-guided isolation of cytotoxic compounds from different sources.