Markers of endothelial dysfunction and arterial stiffness in patients with early-stage autosomal dominant polycystic kidney disease: A meta-analysis.
Ioannis BellosKonstantinos KontzoglouDespina N PerreaPublished in: International journal of clinical practice (2020)
Early-stage ADPKD patients present increased vascular stiffness and endothelial dysfunction, as reflected by low flow-mediated dilatation and elevated values of pulse wave velocity, carotid intima-media thickness and plasma homocysteine. The exact effects of early arterial stiffness on long-term outcomes remain to be elucidated.
Keyphrases
- early stage
- polycystic kidney disease
- blood pressure
- end stage renal disease
- chronic kidney disease
- ejection fraction
- newly diagnosed
- sentinel lymph node
- peritoneal dialysis
- squamous cell carcinoma
- type diabetes
- optical coherence tomography
- radiation therapy
- cardiovascular disease
- patient reported outcomes
- density functional theory
- blood flow
- molecular dynamics