Successful surgical aortic valve replacement in a patient with progeria.
Petar VukovicPetar MilacicIgor S ZivkovicDragana KosevicSlobodan MicovicPublished in: Interactive cardiovascular and thoracic surgery (2022)
The progeroid syndrome includes a group of rare, severe genetic disorders clinically characterized by premature physical ageing. Severe aortic stenosis has been described in progeria patients, but no previous surgical aortic valve replacement was reported. We describe a successful surgical aortic valve replacement combined with coronary artery bypass grafting in a progeria patient with severe aortic stenosis and a small aortic annulus.
Keyphrases
- aortic valve replacement
- aortic stenosis
- ejection fraction
- aortic valve
- transcatheter aortic valve implantation
- transcatheter aortic valve replacement
- coronary artery bypass grafting
- left ventricular
- case report
- coronary artery disease
- early onset
- percutaneous coronary intervention
- end stage renal disease
- mental health
- heart failure
- drug induced
- physical activity
- gene expression
- copy number
- peritoneal dialysis
- patient reported