Can MRI features predict clinically relevant hepatocellular carcinoma genetic subtypes?

Xiaoyang LiuYang GuoLei ZhaoJoseph MisdrajiTina KapurThomas A AbramsPaul B Shyn

Published in: Abdominal radiology (New York) (2023)

An infiltrative tumor margin on MRI correlated with TP53 mutation and peritumoral enhancement correlated with CTNNB1 mutation in HCC. Absence of these MRI features are potential negative predictors of the respective HCC genetic subtypes that have implications for prognosis and treatment response.

Keyphrases

contrast enhanced
magnetic resonance imaging
diffusion weighted imaging
genome wide
computed tomography
magnetic resonance
dna methylation
gene expression
risk assessment