The Distinct Traits of the UNC13A Polymorphism in Amyotrophic Lateral Sclerosis.

Harold H G TanHenk-Jan WestenengHannelore K van der BurghMichael A van EsLeonhard A BakkerKevin van VeenhuijzenKristel R van EijkRuben P A van EijkJan H VeldinkLeonard H van den Berg

Published in: Annals of neurology (2020)

Phenotypical distinctions associated with UNC13A make it an important factor to take into account in clinical trial design, studies on cognition and behavior, and prognostic counseling. ANN NEUROL 2020;88:796-806.

Keyphrases

clinical trial
mild cognitive impairment
genome wide
phase ii
case control
smoking cessation
open label
white matter
double blind
neural network
hiv testing
gene expression
human immunodeficiency virus
hiv infected