Effect of SGRQ-Defined Chronic Bronchitis at Baseline on Treatment Outcomes in Patients with COPD Receiving Nebulized Glycopyrrolate.

Donald P TashkinAyca Ozol-GodfreySanjay Sharma Shahin Sanjar

Published in: International journal of chronic obstructive pulmonary disease (2021)

Treatment with nebulized GLY 25 μg BID for 12 weeks resulted in significant improvements in lung function and SGRQ total scores, compared with placebo. Significant improvements in EXACT-RS total scores were observed only in the CB group. Together, these results support the use of GLY 25 μg BID in patients with COPD, regardless of their CB status.

Keyphrases

lung function
chronic obstructive pulmonary disease
cystic fibrosis
air pollution
density functional theory
double blind
study protocol
replacement therapy
molecular dynamics