The Safety and Efficacy of Quadruple Ultra-Low-Dose Combination (Quadpill) for Hypertension Treatment: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Mohamed AbuelazmShafaqat AliOthman SalehAmr BadrObieda AltobaishatMajd M AlBarakatAya M AboutalebAbdelmonem SiddiqBasel AbdelazeemPublished in: Clinical drug investigation (2023)
The quadruple ultra-low-dose combination of antihypertensive drugs (quadpill) was effective and safe for hypertension treatment. However, further large-scale, multicenter, randomized controlled trials are still warranted before endorsement in clinical practice.