METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE - ASSESSMENT OF PATIENTS WITH OBESITY AND METABOLIC SYNDROME - GUIDELINE FROM THE BRAZILIAN SOCIETY OF BARIATRIC AND METABOLIC SURGERY.
Leonardo Halamy PereiraFernando de BarrosThais Guaraná de AndradeAlvaro Albano de Oliveira NetoCristiane Alves Villela NogueiraAntonio Carlos ValeziPublished in: Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery (2024)
We recommend that every patient undergoing bariatric and metabolic surgery be screened initially with the Fibrosis-4 (FIB-4) score, followed by transient hepatic elastography (vibration-controlled transient elastography, VCTE), especially for those with FIB-4>1.3. However, interpreting VCTE results in obese patients requires further studies to define the actual cutoff values. Enhanced Liver Fibrosis® shows promise but its availability is limited. The indication for liver biopsy during surgery needs to be individualized but it is recommended for those with changes in FIB-4 and/or VCTE. Family screening is recommended for relatives of young patients with already advanced fibrosis. Liver transplantation is an option for patients with advanced MASLD but the optimal timing for bariatric surgery with transplantation is still unclear. Regular follow-up and VCTE examination are recommended to monitor disease progression after surgery.
Keyphrases
- liver fibrosis
- bariatric surgery
- weight loss
- obese patients
- minimally invasive
- metabolic syndrome
- roux en y gastric bypass
- coronary artery bypass
- gastric bypass
- insulin resistance
- surgical site infection
- type diabetes
- cerebral ischemia
- adipose tissue
- percutaneous coronary intervention
- high frequency
- case report
- stem cells
- weight gain
- machine learning
- artificial intelligence
- mesenchymal stem cells
- bone marrow
- brain injury
- blood brain barrier
- middle aged
- big data