Zhi Zi Chi decoction (Gardeniae fructus and semen Sojae Praeparatum) attenuates anxious depression via modulating microbiota-gut-brain axis in corticosterone combined with chronic restraint stress-induced mice.
Xuanhe TianGuangyan WangFei TengXiaoyan XueJin PanQiancheng MaoDongjing GuoXiaobin SongKe MaPublished in: CNS neuroscience & therapeutics (2023)
These findings suggested that ZZCD exerts antidepressant effects pleiotropically through modulating the microbiota-gut-brain.