Olanzapine versus metoclopramide for the treatment of breakthrough chemotherapy-induced vomiting in children: An open-label, randomized phase 3 trial.

Venkatraman RadhakrishnanVishwajeeth PaiSwaminathan RajaramanNikita MehraTrivadi GanesanManikandan DhanushkodiJayachandran Perumal KalaiyarasiArun Kumar RajanGangothri SelvarajanRama RanganathanParathan KarunakaranTenali G Sagar

Published in: Pediatric blood & cancer (2020)

Olanzapine is superior to metoclopramide for the treatment of breakthrough CIV in children. Drowsiness and hyperglycemia need to be monitored closely in children receiving olanzapine for breakthrough CIV.

Keyphrases

chemotherapy induced
young adults
double blind
clinical trial
combination therapy
oxidative stress
smoking cessation