Satisfactory arterial repair 1 year after ultrathin strut biodegradable polymer sirolimus-eluting stent implantation: an angioscopic observation.
Takayuki IshiharaMasaki AwataOsamu IidaMasashi FujitaMasaharu MasudaShin OkamotoKiyonori NantoTakashi KandaTakuya TsujimuraMasaaki UematsuToshiaki ManoPublished in: Cardiovascular intervention and therapeutics (2018)
The ultrathin strut biodegradable polymer sirolimus-eluting stent (Orsiro, O-SES) exhibits satisfactory clinical outcomes. However, no report to date has documented the intravascular status of artery repair after O-SES implantation. We examined 5 O-SES placed in 4 patients (age 65 ± 12 years, male 75%) presenting with stable angina pectoris due to de novo lesions in native coronary arteries. Coronary angioscopy was performed immediately after percutaneous coronary intervention and 1 year later. Angioscopic images were analyzed to determine the following: (1) dominant grade of neointimal coverage (NIC) over the stent; (2) maximum yellow plaque grade; and (3) existence of thrombus. Yellow plaque grade was evaluated both immediately after stent implantation and at the time of follow-up observation. The other parameters were evaluated at the time of follow-up examination. NIC was graded as: grade 0, stent struts exposed; grade 1, struts bulging into the lumen, although covered; grade 2, struts embedded in the neointima, but translucent; grade 3, struts fully embedded and invisible. Yellow plaque severity was graded as: grade 0, white; grade 1, light yellow; grade 2, yellow; and grade 3, intensive yellow. Angioscopic findings at 1 year demonstrated the following: dominant NIC grade 1, grade 2, and grade 3 in 1, 2, and 2 stents, respectively; all stents were covered to some extent; focal thrombus adhesion was observed in only 1 stent. Yellow plaque grade did not change from immediately after stent implantation to follow-up. O-SES demonstrated satisfactory arterial repair 1 year after implantation.
Keyphrases
- coronary artery disease
- percutaneous coronary intervention
- coronary artery
- end stage renal disease
- drug delivery
- healthcare
- heart failure
- chronic kidney disease
- escherichia coli
- acute coronary syndrome
- peritoneal dialysis
- acute myocardial infarction
- case report
- convolutional neural network
- transcatheter aortic valve replacement
- health insurance
- aortic valve
- st elevation myocardial infarction