Regional Differences in the Absolute Abundance of Transporters, Receptors and Tight Junction Molecules at the Blood-Arachnoid Barrier and Blood-Spinal Cord Barrier among Cervical, Thoracic and Lumbar Spines in Dogs.
Hina TakeuchiMasayoshi SuzukiRyohei GotoKenta TezukaHolger FuchsNaoki IshiguroTetsuya TerasakiClemens BraunYasuo UchidaPublished in: Pharmaceutical research (2022)
These results provide a better understanding of the molecular mechanisms underlying the concentration gradients of drugs and endogenous substances in the cerebrospinal fluid and parenchyma of the spinal cord.